General Medicine and Other Clinical Trials

General Medicine

Trial Name	Description	Primary Investigator	Study Details
GS-US-685-6819 RSV	Study to evaluate the efficacy of ODV in reducing the duration of symptoms and to evaluate the safety and tolerability of study drug obeldesivir (ODV; GS-5245) in nonhospitalized adult participants with acute respiratory syncytial virus (RSV) infection. Phase 2 Randomized, Placebo-controlled Study. Sponsor Gilead Sciences	John Carardi, MD	Learn More

Trial Name	Description	Primary Investigator	Study Details
INHANCE	Trial to evaluate the safety and effectiveness of the INHANCE Stemless Reverse shoulder with Reverse Total Shoulder Arthroplasty indicated. The subjects will be randomized to either the Control – INHANCE Stemmed Reverse Total Shoulder or the STUDY – INHANCE Stemless Reverse Total Shoulder group. 2:1 Randomized, Controlled, Multi-Center, Prospective, Pre-Market. Sponsor: DePuy Synthes Products	Paul Favorito, MD	Learn More
Oxinium DH Hip	Brief Trial Description:- The aim of this study is to demonstrate that the OXINIUM DH Hip System is non-inferior to commercially available hip replacement device in Subjects with non-inflammatory degenerative joint disease.- Randomized 1:1 OXINIUM DH Investigational Device in combination with FDA cleared components vs. commercially available hip replacement device	Michael Swank, MD	Learn More
Rotium	This study seeks to evaluate if there is a difference in post-operative healing, strength, and functional outcomes in patients older than 55 years with rotator cuff tears.Rotium, is a nanofiber scaffold that is a FDA approved nonwoven microfiber matrix composed poly L-lactide-co-caprolactone and polyglycolide to enhance healing at the bone tendon interface.Blinded trial and randomization per site is 1:1 surgical repair with scaffold or without scaffold.Sponsor is Atreon Orthopedics, LLC.	Paul Favorito, MD	Learn More

Trial Name	Description	Primary Investigator	Study Details
Caldera Medical 522	This study will evaluate whether the Desara One single incision sling is noninferior to the midurethral Desara Blue TOR implanted via the transobturator approach (outside-in/inside-out) for the treatment of female stress urinary incontinence.The Desara One SIS and Desara Blue TOR are both Class II synthetic surgical mesh products. Non randomized post market study evaluating parallel cohorts. Surgeon determines whether to use the Desara One SIS or the Desara Blue.Sponsor is Caldera Medical.	Mickey Karram, MD	Learn More